Primary Information |
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| BoMiProt ID | Bomi3467 |
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| Protein Name | 26S proteasome non-ATPase regulatory subunit 13/26S proteasome regulatory subunit RPN9/26S proteasome regulatory subunit S11 |
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| Organism | Bos taurus |
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| Uniprot ID | Q5E964 |
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| Milk Fraction | Exosomes |
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| Ref Sequence ID | NP_001019703.1 |
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| Aminoacid Length | 376 |
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| Molecular Weight | 42866 |
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| FASTA Sequence |
Download |
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| Gene Name | PSMD13 |
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| Gene ID | 513525 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Protein Function | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. |
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| Biochemical Properties | Contains 20S core particle (CP) and two 19S regulatory subunits (RP).The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | (1-12) |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | 1.Takeuchi, J., Fujimuro, M., Yokosawa, H., Tanaka, K., & Toh-e, A. (1999). Rpn9 is required for efficient assembly of the yeast 26S proteasome. Molecular and cellular biology, 19(10), 6575–6584. https://doi.org/10.1128/MCB.19.10.6575 |
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