Primary Information |
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| BoMiProt ID | Bomi3732 |
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| Protein Name | ADP/ATP translocase 3/Solute carrier family 25 member 6/Adenine nucleotide translocator 3 |
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| Organism | Bos taurus |
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| Uniprot ID | P32007 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_777085.1 |
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| Aminoacid Length | 298 |
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| Molecular Weight | 32877 |
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| FASTA Sequence |
Download |
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| Gene Name | SLC25A6 |
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| Gene ID | 282480 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Presence in other biological fluids/tissue/cells | rumen papilla |
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| Protein Function | Adenine nucleotide translocase (ANT) 3, an enzyme which exchanges ATP and ADP through mitochondrial membrane, has been identified as a novel target counter-regulated by IL-4 and IFN-gamma. |
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| PTMs | N-acetylation at methionine,Trimethylation by ANTKMT at Lys-52 |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | 4-7, 40-53, 243-245 |
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| DisProt Annotation | |
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| TM Helix Prediction | 2TMHs; (173-195),(210-231) |
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| Additional Comments | Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells |
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| Bibliography | 1.Jang JY, Lee CE. Mitochondrial adenine nucleotide translocator 3 is regulated by IL-4 and IFN-gamma via STAT-dependent pathways. Cell Immunol. 2003 Nov;226(1):11-9. doi: 10.1016/j.cellimm.2003.11.004. PMID: 14746803. 2.Zamora M, Granell M, Mampel T, Viñas O. Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells. FEBS Lett. 2004 Apr 9;563(1-3):155-60. doi: 10.1016/S0014-5793(04)00293-5. PMID: 15063741. |
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