Primary Information |
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| BoMiProt ID | Bomi6055 |
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| Protein Name | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific/Spermatogenic glyceraldehyde-3-phosphate dehydrogenase |
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| Organism | Bos taurus |
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| Uniprot ID | Q2KJE5 |
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| Milk Fraction | Exosomes |
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| Ref Sequence ID | NP_001035642.1 |
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| Aminoacid Length | 395 |
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| Molecular Weight | 43288 |
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| FASTA Sequence |
Download |
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| Gene Name | GAPDHS |
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| Gene ID | 532231 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Presence in other biological fluids/tissue/cells | myometrium |
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| Protein Function | Resistance to inhibitors of cholinesterase 8A (Ric-8A) is a prominent non-receptor GEF and a chaperone of G protein α-subunits (Gα). |
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| Biochemical Properties | Ric-8A is composed of a core armadillo-like domain and a flexible C-terminal tail. Interaction of a conserved concave surface of its core domain with the Gα C-terminus appears to mediate formation of the initial Ric-8A/GαGDP intermediate, followed by the formation of a stable nucleotide-free complex. |
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| PTMs | Phosphorylation at Ser/thr |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | 1-59, |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | 1.Srivastava D, Artemyev NO. Ric-8A, a GEF, and a Chaperone for G Protein α-Subunits: Evidence for the Two-Faced Interface. Bioessays. 2020 Mar;42(3):e1900208. doi: 10.1002/bies.201900208. Epub 2020 Jan 22. PMID: 31967346; PMCID: PMC7034654. |
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