Primary Information |
|---|
| BoMiProt ID | Bomi6491 |
|---|
| Protein Name | Interleukin-17A |
|---|
| Organism | Bos taurus |
|---|
| Uniprot ID | Q687Y7 |
|---|
| Milk Fraction | Whey |
|---|
| Ref Sequence ID | NP_001008412.1 |
|---|
| Aminoacid Length | 153 |
|---|
| Molecular Weight | 17242 |
|---|
| FASTA Sequence |
Download |
|---|
| Gene Name | IL17A |
|---|
| Gene ID | 282863 |
|---|
| Protein Existence Status | reviewed |
|---|
Secondary Information |
|---|
| Protein Function | cytokine activity,inflammation,host defense |
|---|
| Biochemical Properties | highly conserved C-terminus containing a cysteine-knot fold structure |
|---|
| Significance in milk | Act as biomarker for Bovine Tuberculosis |
|---|
| PTMs | Disulfide bond formation,Glycosylation |
|---|
Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q687Y7|IL17_BOVIN Interleukin-17A OS=Bos taurus OX=9913 GN=IL17A PE=2 SV=1
MASMRTSSMSLLLLLSLVALVKAGVIIPQSPGCPPTEDKNFPQHVRVNLNIVN*53RSTNSRR
PTDYHKRSTSPWTLHRNEDPERYPSVIWEAKCSHSGCINAEGKVDHHMNSVTIQQEILVL
RRESQHCPHSFRLEKMLVAVGCTCVTPIVRHLA
|
|---|
| Predicted Disorder Regions | 3 disordered segments; (1-6), (29-44), (50-73) |
|---|
| DisProt Annotation | |
|---|
| TM Helix Prediction | No TM helices |
|---|
| Bibliography | Chen K, Kolls JK. Interluekin-17A (IL17A). Gene. 2017 May 30;614:8-14. doi: 10.1016/j.gene.2017.01.016. Epub 2017 Jan 22. PMID: 28122268; PMCID: PMC5394985. |
|---|
