Primary Information |
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| BoMiProt ID | Bomi8099 |
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| Protein Name | Pleiotropic regulator 1 |
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| Organism | Bos taurus |
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| Uniprot ID | Q2KID6 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001039827.1 |
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| Aminoacid Length | 513 |
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| Molecular Weight | 56789 |
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| FASTA Sequence |
Download |
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| Gene Name | PLRG1 |
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| Gene ID | 533951 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| PTMs | N-Acetylation at Meth, Phosphorylation at Ser |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q2KID6|PLRG1_BOVIN Pleiotropic regulator 1 OS=Bos taurus OX=9913 GN=PLRG1 PE=2 SV=1
MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
SKENLKEKVPQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALTADTKIQRMPS*119E
SAAQSLAVALPASQARADANRPVPAGGEYRHPGAPDRAQPAGAVVMEGSNAKNSALMAKK
APTMPKPQWHPPWKLYRVIS*200GHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLS
LTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTID
VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVA
GKTRVTLTNHKKSVRAVVLHPRHYTFASGS*390PDNIKQWKFPDGSFIQNLSGHNAIINTLTV
NSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAE
ADKTIKVYKEDDTATEETHPVSWKPEIIKRKRF
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| Predicted Disorder Regions | 29-36, 59-160 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Additional Comments | The NF-κB (nuclear factor κB) transcription factor family is a pleiotropic regulator of many cellular pathways, providing a mechanism for the cell to respond to a wide variety of stimuli and environmental challenges. |
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| Bibliography | 1.Ledoux AC, Perkins ND. NF-κB and the cell cycle. Biochem Soc Trans. 2014 Feb;42(1):76-81. doi: 10.1042/BST20130156. PMID: 24450631. |
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