Primary Information |
|---|
| BoMiProt ID | Bomi8605 |
|---|
| Protein Name | Ragulator complex protein LAMTOR1/Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1 |
|---|
| Organism | Bos taurus |
|---|
| Uniprot ID | Q3T0D8 |
|---|
| Milk Fraction | Whey |
|---|
| Ref Sequence ID | NP_001029941.1 |
|---|
| Aminoacid Length | 161 |
|---|
| Molecular Weight | 17731 |
|---|
| FASTA Sequence |
Download |
|---|
| Gene Name | LAMTOR1 |
|---|
| Gene ID | 614849 |
|---|
| Protein Existence Status | Reviewed |
|---|
Secondary Information |
|---|
| Presence in other biological fluids/tissue/cells | pons |
|---|
| Protein Function | It acts as a part of the ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. |
|---|
| PTMs | Myristoylation, Phosphorylation at Ser |
|---|
Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q3T0D8|LTOR1_BOVIN Ragulator complex protein LAMTOR1 OS=Bos taurus OX=9913 GN=LAMTOR1 PE=2 SV=1
MGCCYSSENEDSDQDREERKLLLDPSS*27PPTKALNGAEPNYHS*42LPSARTDEQALLSS*56ILAK
TASNIIDVSAADSQGMEQHEYMDRARQYSTRLAVLSSS*98LTHWKKLPPLPSLTSQPHQVLA
SEPVPFSDLQQVSRIAAYAYS*141ALSQIRVDAKEELVVQFGIP
|
|---|
| Predicted Disorder Regions | 1-52, 71-87, 107-124 |
|---|
| DisProt Annotation | |
|---|
| TM Helix Prediction | No TM helices |
|---|
