Primary Information |
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| BoMiProt ID | Bomi9287 |
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| Protein Name | Sodium-driven chloride bicarbonate exchanger/Solute carrier family 4 member 10 |
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| Organism | Bos taurus |
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| Uniprot ID | Q32LP4 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001033217.1 |
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| Aminoacid Length | 1117 |
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| Molecular Weight | 125776 |
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| FASTA Sequence |
Download |
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| Gene Name | SLC4A10 |
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| Gene ID | 517077 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Acts as Na+-coupled Cl−–HCO3 − exchanger.drastically reduces brain ventricle volume and protects against fatal epileptic seizures in mice.Also involved in control of neuronal pH and excitability and may contribute to the secretion of cerebrospinal fluid. |
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| PTMs | Glycosylation, Phosphorylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q32LP4|S4A10_BOVIN Sodium-driven chloride bicarbonate exchanger OS=Bos taurus OX=9913 GN=SLC4A10 PE=2 SV=1
MQSGTCESFQSLSHQRNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKS
HRRHRHRGHKHRKRDRERDSGLEDGRES*88PSFDT*93PSQRVQFILGTEDDDEEHIPHDLFTEL
DEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLL
DMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFAD
IGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVS*275RENSTVDFSKGLGGQQKGHTSPCGM
KQRHEKGPPHQQDREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGL
AEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFL
DQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSGPELQRTGR
LFGGLILDIKRKAPYFWSDFTDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISA
IESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWT
ATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLEL
LTQYSCNCVEPHN*673PSN*676NTLKEWRESN*686ISASDIIWEN*696LTVSECTSLHGEYVGRACGHEHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGI
PSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINR
KEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQP
KFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKL
FWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRK
LMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQS*1056MLAMEDEGTVQLPLEGHYRDDPSV
INIS*1084DEMSKTALWRNLLITADNSKDKESSFPSKSSPS |
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| Predicted Disorder Regions | 1-10, 55-106, 259-267, 290-306, 466-472, 1052-1063, 1105-1117 |
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| DisProt Annotation | |
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| TM Helix Prediction | 11TMH; (509-531), (544-566), ( 597-619), (626-644), (724-742), (762-780), (810-828), (848-870), (911-929), ( 936-954), (996-1018) |
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